SPRO – Spero Therapeutics, Inc.
SPRO — Price & Float Short
—— Fair value
★ EPS beat
★ EPS miss
—— Target Price
Float Short %
Float Short %
2.75
Margin Of Safety %
12
Put/Call OI Ratio
0.05
EPS Next Q Diff
EPS Last/This Y
0.52
EPS This/Next Y
0.09
Price
2.76
Target Price
4
Analyst Recom
3
Performance Q
23.21
Upside
91.3%
Beta
1.44
Ticker: SPRO
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| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
|---|---|---|---|---|---|
| 2026-04-24 | SPRO | 2.75 | 0.14 | 0.00 | 11547 |
| 2026-04-27 | SPRO | 2.67 | 0.14 | 0.00 | 11733 |
| 2026-04-28 | SPRO | 2.68 | 0.14 | 0.00 | 11879 |
| 2026-04-29 | SPRO | 2.54 | 0.13 | 0.20 | 11952 |
| 2026-04-30 | SPRO | 2.52 | 0.14 | 0.12 | 12273 |
| 2026-05-01 | SPRO | 2.47 | 0.14 | 0.00 | 12398 |
| 2026-05-04 | SPRO | 2.51 | 0.13 | 1.74 | 12590 |
| 2026-05-05 | SPRO | 2.43 | 0.15 | 0.24 | 12928 |
| 2026-05-06 | SPRO | 2.54 | 0.16 | 0.05 | 12927 |
| 2026-05-07 | SPRO | 2.51 | 0.15 | 0.00 | 13568 |
| 2026-05-08 | SPRO | 2.57 | 0.15 | 0.03 | 13597 |
| 2026-05-11 | SPRO | 2.56 | 0.15 | 0.00 | 13645 |
| 2026-05-12 | SPRO | 2.54 | 0.14 | 0.36 | 14383 |
| 2026-05-13 | SPRO | 2.43 | 0.15 | 0.03 | 14935 |
| 2026-05-14 | SPRO | 2.76 | 0.14 | 0.10 | 15532 |
| 2026-05-15 | SPRO | 2.8 | 0.13 | 0.02 | 16619 |
| 2026-05-18 | SPRO | 2.57 | 0.06 | 0.01 | 16347 |
| 2026-05-19 | SPRO | 2.58 | 0.06 | 0.00 | 16673 |
| 2026-05-20 | SPRO | 2.62 | 0.05 | 0.00 | 17851 |
| 2026-05-21 | SPRO | 2.68 | 0.05 | 0.00 | 18399 |
| 2026-05-22 | SPRO | 2.76 | 0.05 | 0.00 | 18591 |
| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
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| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
|---|---|---|---|---|---|
| 2026-04-24 | SPRO | 2.74 | - | - | 0.67 |
| 2026-04-27 | SPRO | 2.68 | - | - | 0.67 |
| 2026-04-28 | SPRO | 2.67 | - | - | 0.67 |
| 2026-04-30 | SPRO | 2.52 | - | - | 0.67 |
| 2026-05-01 | SPRO | 2.48 | - | - | 0.67 |
| 2026-05-04 | SPRO | 2.50 | - | - | 0.67 |
| 2026-05-05 | SPRO | 2.42 | - | - | 0.67 |
| 2026-05-06 | SPRO | 2.53 | - | - | 0.67 |
| 2026-05-07 | SPRO | 2.52 | - | - | 0.67 |
| 2026-05-08 | SPRO | 2.57 | - | - | 0.67 |
| 2026-05-11 | SPRO | 2.55 | - | - | 0.67 |
| 2026-05-12 | SPRO | 2.55 | - | - | 0.67 |
| 2026-05-13 | SPRO | 2.43 | - | - | 0.67 |
| 2026-05-14 | SPRO | 2.76 | - | - | 0.67 |
| 2026-05-15 | SPRO | 2.80 | - | - | 0.67 |
| 2026-05-18 | SPRO | 2.58 | - | - | 0.67 |
| 2026-05-19 | SPRO | 2.58 | - | - | 0.67 |
| 2026-05-20 | SPRO | 2.62 | - | - | 0.67 |
| 2026-05-21 | SPRO | 2.68 | - | - | 0.67 |
| 2026-05-22 | SPRO | 2.76 | - | - | 0.67 |
| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
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| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
|---|---|---|---|---|
| 2026-04-24 | SPRO | -1.34 | 1.21 | 1.43 |
| 2026-04-27 | SPRO | -1.34 | 1.24 | 1.74 |
| 2026-04-28 | SPRO | -1.34 | 1.24 | 1.74 |
| 2026-04-29 | SPRO | -1.34 | 1.24 | 1.74 |
| 2026-04-30 | SPRO | -1.34 | 1.24 | 1.74 |
| 2026-05-01 | SPRO | -1.34 | 1.24 | 1.74 |
| 2026-05-04 | SPRO | -1.34 | 1.18 | 1.74 |
| 2026-05-05 | SPRO | -1.34 | 1.18 | 1.74 |
| 2026-05-06 | SPRO | -1.34 | 1.18 | 1.74 |
| 2026-05-07 | SPRO | -1.50 | 1.18 | 1.74 |
| 2026-05-08 | SPRO | -1.50 | 1.18 | 1.74 |
| 2026-05-11 | SPRO | -1.50 | 0.89 | 1.72 |
| 2026-05-12 | SPRO | -1.56 | 0.89 | 2.75 |
| 2026-05-13 | SPRO | -1.30 | 0.89 | 2.75 |
| 2026-05-14 | SPRO | -1.30 | 0.89 | 2.75 |
| 2026-05-15 | SPRO | -1.30 | 0.89 | 2.75 |
| 2026-05-18 | SPRO | -1.30 | 0.98 | 2.75 |
| 2026-05-19 | SPRO | -1.30 | 0.98 | 2.75 |
| 2026-05-20 | SPRO | -1.30 | 0.98 | 2.75 |
| 2026-05-21 | SPRO | -1.30 | 0.98 | 2.75 |
| 2026-05-22 | SPRO | -1.30 | 0.98 | 2.75 |
| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
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Last Quarter Act. EPS
Avg. EPS Est. Current Quarter
-0.2
Avg. EPS Est. Next Quarter
Insider Transactions
-1.3
Institutional Transactions
0.98
Beta
1.44
Average Sales Estimate Current Quarter
Average Sales Estimate Next Quarter
Fair Value
3.08
Quality Score
71
Growth Score
51
Sentiment Score
93
Actual DrawDown %
86.1
Max Drawdown 5-Year %
-97.1
Target Price
4
P/E
11.33
Forward P/E
3.63
PEG
P/S
2.92
P/B
3.02
P/Free Cash Flow
22.07
EPS
0.24
Average EPS Est. Cur. Y
0.67
EPS Next Y. (Est.)
0.76
Target Price Estimates Raised
Target Price Estimates Lowered
Profit Margin
27.82
Relative Volume
1.24
Return on Equity vs Sector %
1.7
Return on Equity vs Industry %
17.3
EPS 1 7Days Diff
EPS 1 30Days Diff
EBIT Estimation
◆
SPRO
Healthcare
$2.76
📉
Swing / Pullback
Buy the dip on strong trends
WATCH
Trend
20/20
Pullback
10/25
Volume
4/15
Valuation
17/20
TP/AR
0/10
Options
8/10
RSI
57.8
Range 1M
75.9%
Sup Dist
5.8%
🚀
N/A
Momentum Growth
Ride accelerating trends
WEAK
Momentum
19/25
Growth
15/30
Estimates
4/20
Inst/Vol
9/15
Options
6/10
EPS Yr
346.7%
EPS NY
13.4%
52W%
82.8%
💎
N/A
Long-Term Value
Quality companies, undervalued
WEAK
🟢 BUY
+265.4% upside
Quality
17/30
Valuation
23/30
Growth
13/25
Stability
7/10
LT Trend
4/5
Upside
+265.4%
Quality
71
MoS
12%
Click a card to see score breakdown
Full Analysis →
Sector: Healthcare
Industry: Biotechnology
Employees: 25
Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.
SPRO
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