Spero Therapeutics, Inc.

SPRO

$1.02

Name : Spero Therapeutics, Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $59,399,524.00

EPSttm : 0.14

Spero Therapeutics, Inc.

$1.02

0.99%

$0.01

SPRO — Price & Float Short

—— Fair value ★ EPS beat ★ EPS miss —— Target Price

Float Short %

1.83

Margin Of Safety %

Put/Call OI Ratio

0.42

EPS Next Q Diff

EPS Last/This Y

-0.73

EPS This/Next Y

0.47

Price

1.03

Target Price

Analyst Recom

Performance Q

-17.74

Upside

40.2%

Beta

1.57

Ticker: SPRO

22 items of 1

Date	Symbol	Latest	P/C OI	P/C Vol	Total OI
2026-10-13	SPRO	1.15	0.26	1.57	8693
2026-10-14	SPRO	1.11	0.26	3.40	8688
2026-10-15	SPRO	1.135	0.26	5.00	8670
2026-10-16	SPRO	1.105	0.26	999.99	8666
2026-10-19	SPRO	1.125	0.45	0.00	3827
2026-10-20	SPRO	1.22	0.45	3.20	3837
2026-10-21	SPRO	1.175	0.45	999.99	3853
2026-10-22	SPRO	1.135	0.45	999.99	3854
2026-10-23	SPRO	1.11	0.45	0.90	3854
2026-10-26	SPRO	1.065	0.45	2.33	3832
2026-10-27	SPRO	1.12	0.44	0.09	3813
2026-10-28	SPRO	1.17	0.42	0.90	3916
2026-10-29	SPRO	1.115	0.42	0.18	3909
2026-10-30	SPRO	1.06	0.41	0.60	3958
2026-11-02	SPRO	1.04	0.41	22.00	3963
2026-11-03	SPRO	1.0462	0.41	24.00	3967
2026-11-04	SPRO	1.06	0.41	7.00	3970
2026-11-05	SPRO	1.01	0.42	1.18	3972
2026-11-06	SPRO	1.035	0.41	5.33	3994
2026-11-09	SPRO	1.07	0.41	1.65	3994
2026-11-10	SPRO	1.03	0.41	19.00	3994
2026-11-11	SPRO	1.02	0.42	106.00	4006
Date	Symbol	Latest	P/C OI	P/C Vol	Total OI

22 items 1 of 1

22 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2026-10-13	SPRO	1.16	-	-	-0.58
2026-10-14	SPRO	1.11	-	-	-0.58
2026-10-15	SPRO	1.13	-	-	-0.58
2026-10-16	SPRO	1.10	-	-	-0.58
2026-10-19	SPRO	1.12	-	-	-0.58
2026-10-20	SPRO	1.12	-	-	-0.58
2026-10-21	SPRO	1.22	-	-	-0.58
2026-10-22	SPRO	1.13	-	-	-0.58
2026-10-23	SPRO	1.11	-	-	-0.58
2026-10-26	SPRO	1.07	-	-	-0.58
2026-10-27	SPRO	1.13	-	-	-0.58
2026-10-28	SPRO	1.17	-	-	-0.58
2026-10-29	SPRO	1.12	-	-	-0.58
2026-10-30	SPRO	1.07	-	-	-0.58
2026-11-02	SPRO	1.05	-	-	-0.58
2026-11-03	SPRO	1.04	-	-	-0.58
2026-11-04	SPRO	1.06	-	-	-0.58
2026-11-05	SPRO	1.01	-	-	-0.58
2026-11-06	SPRO	1.03	-	-	-0.58
2026-11-09	SPRO	1.08	-	-	-0.58
2026-11-10	SPRO	1.01	-	-	-0.58
2026-11-11	SPRO	1.03	-	-	-0.58
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

22 items 1 of 1

21 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2026-10-13	SPRO	-0.17	1.76	1.85
2026-10-14	SPRO	-0.17	1.76	1.85
2026-10-15	SPRO	-0.17	1.76	1.85
2026-10-16	SPRO	-0.17	1.76	1.85
2026-10-19	SPRO	-0.17	1.63	1.85
2026-10-20	SPRO	-0.17	1.63	1.85
2026-10-21	SPRO	-0.17	1.63	1.85
2026-10-22	SPRO	-0.17	1.63	1.85
2026-10-23	SPRO	-0.17	1.63	1.85
2026-10-26	SPRO	-0.17	1.65	1.85
2026-10-27	SPRO	-0.17	1.65	1.96
2026-10-28	SPRO	-0.17	1.65	1.96
2026-10-29	SPRO	-0.17	1.65	1.96
2026-10-30	SPRO	-0.17	1.65	1.96
2026-11-02	SPRO	-0.17	1.47	1.96
2026-11-03	SPRO	-0.17	1.47	1.96
2026-11-05	SPRO	-0.17	1.47	1.96
2026-11-06	SPRO	-0.17	1.47	1.96
2026-11-09	SPRO	0.00	4.80	1.96
2026-11-10	SPRO	0.00	4.80	1.96
2026-11-11	SPRO	-0.27	4.80	1.83
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

21 items 1 of 1

Last Quarter Act. EPS

Avg. EPS Est. Current Quarter

-0.14

Avg. EPS Est. Next Quarter

-0.14

Insider Transactions

-0.27

Institutional Transactions

4.8

Beta

1.57

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

1.59

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

-96.7

Target Price

P/E

9.34

Forward P/E

PEG

P/S

1.38

P/B

1.34

P/Free Cash Flow

3.03

EPS

0.11

Average EPS Est. Cur. Y

-0.58

EPS Next Y. (Est.)

-0.1

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

17.18

Relative Volume

0.27

Return on Equity vs Sector %

-9.7

Return on Equity vs Industry %

9.9

EPS 1 7Days Diff

-0.3

EPS 1 30Days Diff

-0.29

EBIT Estimation

◆ SPRO Healthcare

$1.02

📉

Swing / Pullback

Buy the dip on strong trends

N/A

WEAK

Trend

8/20

Pullback

19/25

Volume

11/15

Valuation

15/20

TP/AR

4/10

Options

5/10

RSI

41.2

Range 1M

21.2%

Sup Dist

2.9%

🚀

Momentum Growth

Ride accelerating trends

N/A

WEAK

Momentum

3/25

Growth

5/30

Estimates

7/20

Inst/Vol

4/15

Options

6/10

EPS Yr

-746.7%

EPS NY

4.1%

52W%

2.8%

💎

Long-Term Value

Quality companies, undervalued

N/A

WEAK

🟢 BUY +228.8% upside

Quality

9/30

Valuation

23/30

Growth

2/25

Stability

7/10

LT Trend

1/5

Upside

+228.8%

Quality

MoS

55%

SPRO — P/E HistoricalBiotechnology

Spero Therapeutics, Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 25

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

SPRO

Latest News

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Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Upside

Beta

Ticker: SPRO

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Latest News

Last Quarter Act. EPS

Average EPS Est. Cur. Y