Spero Therapeutics, Inc.

SPRO

$2.57

Name : Spero Therapeutics, Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $148,806,832.00

EPSttm : 0.27

Spero Therapeutics, Inc.

$2.57

6.20%

$0.17

SPRO — Price & Float Short

—— Fair value ★ EPS beat ★ EPS miss —— Target Price

Float Short %

3.84

Margin Of Safety %

Put/Call OI Ratio

0.07

EPS Next Q Diff

EPS Last/This Y

0.52

EPS This/Next Y

0.09

Price

2.58

Target Price

Analyst Recom

Performance Q

4.9

Upside

105.4%

Beta

1.46

Ticker: SPRO

20 items of 1

Date	Symbol	Latest	P/C OI	P/C Vol	Total OI
2026-05-11	SPRO	2.56	0.15	0.00	13645
2026-05-12	SPRO	2.54	0.14	0.36	14383
2026-05-13	SPRO	2.43	0.15	0.03	14935
2026-05-14	SPRO	2.76	0.14	0.10	15532
2026-05-15	SPRO	2.8	0.13	0.02	16619
2026-05-18	SPRO	2.57	0.06	0.01	16347
2026-05-19	SPRO	2.58	0.06	0.00	16673
2026-05-20	SPRO	2.62	0.05	0.00	17851
2026-05-21	SPRO	2.68	0.05	0.00	18399
2026-05-22	SPRO	2.76	0.05	0.00	18591
2026-05-26	SPRO	2.87	0.05	0.00	18994
2026-05-27	SPRO	2.93	0.05	0.00	19105
2026-05-28	SPRO	2.91	0.05	1.52	19789
2026-05-29	SPRO	2.82	0.07	0.00	20537
2026-06-02	SPRO	2.84	0.07	0.00	21565
2026-06-03	SPRO	2.8	0.07	0.01	21772
2026-06-04	SPRO	2.97	0.06	0.59	22141
2026-06-05	SPRO	2.83	0.08	0.01	22781
2026-06-08	SPRO	2.74	0.08	0.46	23088
2026-06-09	SPRO	2.57	0.07	0.28	23364
Date	Symbol	Latest	P/C OI	P/C Vol	Total OI

20 items 1 of 1

21 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2026-05-11	SPRO	2.55	-	-	0.67
2026-05-12	SPRO	2.55	-	-	0.67
2026-05-13	SPRO	2.43	-	-	0.67
2026-05-14	SPRO	2.76	-	-	0.67
2026-05-15	SPRO	2.80	-	-	0.67
2026-05-18	SPRO	2.58	-	-	0.67
2026-05-19	SPRO	2.58	-	-	0.67
2026-05-20	SPRO	2.62	-	-	0.67
2026-05-21	SPRO	2.68	-	-	0.67
2026-05-22	SPRO	2.76	-	-	0.67
2026-05-26	SPRO	2.87	-	-	0.67
2026-05-27	SPRO	2.93	-	-	0.67
2026-05-28	SPRO	2.91	-	-	0.67
2026-05-29	SPRO	2.83	-	-	0.67
2026-06-01	SPRO	2.83	-	-	0.67
2026-06-02	SPRO	2.85	-	-	0.67
2026-06-03	SPRO	2.80	-	-	0.67
2026-06-04	SPRO	2.98	-	-	0.67
2026-06-05	SPRO	2.83	-	-	0.67
2026-06-08	SPRO	2.75	-	-	0.67
2026-06-09	SPRO	2.58	-	-	0.67
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

21 items 1 of 1

20 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2026-05-11	SPRO	-1.50	0.89	1.72
2026-05-12	SPRO	-1.56	0.89	2.75
2026-05-13	SPRO	-1.30	0.89	2.75
2026-05-14	SPRO	-1.30	0.89	2.75
2026-05-15	SPRO	-1.30	0.89	2.75
2026-05-18	SPRO	-1.30	0.98	2.75
2026-05-19	SPRO	-1.30	0.98	2.75
2026-05-20	SPRO	-1.30	0.98	2.75
2026-05-21	SPRO	-1.30	0.98	2.75
2026-05-22	SPRO	-1.30	0.98	2.75
2026-05-26	SPRO	-1.30	-0.91	2.75
2026-05-27	SPRO	-1.30	-0.91	2.75
2026-05-28	SPRO	-1.30	-0.91	3.84
2026-05-29	SPRO	-1.30	-0.91	3.84
2026-06-02	SPRO	-1.30	-1.55	3.84
2026-06-03	SPRO	-1.30	-1.55	3.84
2026-06-04	SPRO	-1.30	-1.55	3.84
2026-06-05	SPRO	-1.30	-1.55	3.84
2026-06-08	SPRO	-1.30	-1.55	3.84
2026-06-09	SPRO	-1.30	-1.55	3.84
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

20 items 1 of 1

Last Quarter Act. EPS

Avg. EPS Est. Current Quarter

-0.2

Avg. EPS Est. Next Quarter

Insider Transactions

-1.3

Institutional Transactions

-1.55

Beta

1.46

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

3.16

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

-97.1

Target Price

P/E

10.55

Forward P/E

3.38

PEG

P/S

2.72

P/B

2.81

P/Free Cash Flow

20.55

EPS

0.24

Average EPS Est. Cur. Y

0.67

EPS Next Y. (Est.)

0.76

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

27.82

Relative Volume

2.05

Return on Equity vs Sector %

1.3

Return on Equity vs Industry %

17.5

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

◆ SPRO Healthcare

$2.57

📉

Swing / Pullback

Buy the dip on strong trends

N/A

WEAK

Trend

6/20

Pullback

9/25

Volume

3/15

Valuation

18/20

TP/AR

0/10

Options

8/10

RSI

42.8

Range 1M

37.3%

🚀

Momentum Growth

Ride accelerating trends

N/A

WEAK

Momentum

4/25

Growth

15/30

Estimates

4/20

Inst/Vol

4/15

Options

8/10

EPS Yr

346.7%

EPS NY

13.4%

52W%

58.8%

💎

Long-Term Value

Quality companies, undervalued

N/A

WEAK

🟢 BUY +293.3% upside

Quality

17/30

Valuation

24/30

Growth

13/25

Stability

6/10

LT Trend

0/5

Upside

+293.3%

Quality

MoS

22%

Spero Therapeutics, Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 25

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

SPRO

Latest News

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Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Upside

Beta

Ticker: SPRO

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Latest News

Last Quarter Act. EPS

Average EPS Est. Cur. Y