DNLI – Denali Therapeutics Inc.
DNLI — Price & Float Short
—— Fair value
★ EPS beat
★ EPS miss
—— Target Price
Float Short %
Float Short %
10.46
Margin Of Safety %
Put/Call OI Ratio
0.38
EPS Next Q Diff
0.05
EPS Last/This Y
0.62
EPS This/Next Y
-0.21
Price
19.47
Target Price
35.27
Analyst Recom
1.16
Performance Q
-1.82
Upside
-292.4%
Beta
1
Ticker: DNLI
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| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
|---|---|---|---|---|---|
| 2026-04-13 | DNLI | 19.4 | 0.53 | 0.44 | 13994 |
| 2026-04-14 | DNLI | 20.16 | 0.53 | 0.39 | 13931 |
| 2026-04-15 | DNLI | 21.71 | 0.53 | 0.02 | 13939 |
| 2026-04-16 | DNLI | 20.7 | 0.54 | 1.84 | 13880 |
| 2026-04-17 | DNLI | 20.56 | 0.53 | 0.10 | 13894 |
| 2026-04-20 | DNLI | 20.54 | 0.28 | 0.00 | 7476 |
| 2026-04-21 | DNLI | 20.13 | 0.28 | 2.15 | 7486 |
| 2026-04-22 | DNLI | 20.25 | 0.29 | 0.21 | 7607 |
| 2026-04-23 | DNLI | 19.45 | 0.29 | 1.65 | 7643 |
| 2026-04-24 | DNLI | 19.87 | 0.30 | 1.00 | 7711 |
| 2026-04-27 | DNLI | 19.96 | 0.30 | 0.02 | 7788 |
| 2026-04-28 | DNLI | 20.07 | 0.30 | 2.00 | 7778 |
| 2026-04-29 | DNLI | 18.97 | 0.30 | 6.22 | 7780 |
| 2026-04-30 | DNLI | 18.71 | 0.36 | 0.75 | 8170 |
| 2026-05-01 | DNLI | 18.3 | 0.36 | 0.88 | 8174 |
| 2026-05-04 | DNLI | 18.68 | 0.37 | 4.09 | 8184 |
| 2026-05-05 | DNLI | 18.92 | 0.37 | 6.34 | 8229 |
| 2026-05-06 | DNLI | 20.4 | 0.39 | 0.11 | 8344 |
| 2026-05-07 | DNLI | 19.74 | 0.33 | 0.56 | 9661 |
| 2026-05-08 | DNLI | 19.61 | 0.36 | 0.60 | 9756 |
| 2026-05-11 | DNLI | 19.68 | 0.36 | 1.58 | 9912 |
| 2026-05-12 | DNLI | 19.46 | 0.38 | 8.49 | 9969 |
| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
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| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
|---|---|---|---|---|---|
| 2026-04-13 | DNLI | 19.41 | 10.4 | 133.1 | -2.47 |
| 2026-04-14 | DNLI | 20.16 | 10.4 | 110.7 | -2.47 |
| 2026-04-15 | DNLI | 21.71 | 10.4 | 64.5 | -2.47 |
| 2026-04-16 | DNLI | 20.70 | 10.4 | 94.6 | -2.47 |
| 2026-04-17 | DNLI | 20.56 | 10.4 | 99.0 | -2.47 |
| 2026-04-20 | DNLI | 20.56 | 10.4 | 98.7 | -2.47 |
| 2026-04-21 | DNLI | 20.11 | 9.4 | 112.2 | -2.55 |
| 2026-04-22 | DNLI | 20.25 | 9.4 | 108.1 | -2.55 |
| 2026-04-23 | DNLI | 19.46 | 9.4 | 131.2 | -2.55 |
| 2026-04-24 | DNLI | 19.89 | 9.4 | 118.4 | -2.55 |
| 2026-04-27 | DNLI | 19.96 | 9.4 | 116.5 | -2.55 |
| 2026-04-28 | DNLI | 20.07 | 9.4 | 113.2 | -2.55 |
| 2026-04-30 | DNLI | 18.70 | 9.4 | 154.0 | -2.55 |
| 2026-05-01 | DNLI | 18.29 | 9.4 | 166.1 | -2.55 |
| 2026-05-04 | DNLI | 18.67 | 9.4 | 155.1 | -2.55 |
| 2026-05-05 | DNLI | 18.92 | 9.4 | 147.2 | -2.55 |
| 2026-05-06 | DNLI | 20.39 | 9.4 | 111.5 | -2.55 |
| 2026-05-07 | DNLI | 19.71 | 9.4 | 123.9 | -2.55 |
| 2026-05-08 | DNLI | 19.61 | 9.4 | 126.7 | -2.55 |
| 2026-05-11 | DNLI | 19.68 | 9.6 | - | -2.54 |
| 2026-05-12 | DNLI | 19.47 | 26.2 | - | -2.35 |
| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
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| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
|---|---|---|---|---|
| 2026-04-14 | DNLI | -0.31 | 8.39 | 10.90 |
| 2026-04-15 | DNLI | -0.31 | 8.39 | 10.90 |
| 2026-04-16 | DNLI | -0.31 | 8.39 | 10.90 |
| 2026-04-17 | DNLI | -0.31 | 8.39 | 10.90 |
| 2026-04-20 | DNLI | -0.31 | 8.33 | 10.90 |
| 2026-04-21 | DNLI | -0.31 | 8.33 | 10.90 |
| 2026-04-22 | DNLI | -0.31 | 8.33 | 10.88 |
| 2026-04-23 | DNLI | -0.31 | 8.33 | 10.88 |
| 2026-04-24 | DNLI | -0.31 | 8.33 | 10.88 |
| 2026-04-27 | DNLI | -0.31 | 7.63 | 10.80 |
| 2026-04-28 | DNLI | -0.31 | 7.63 | 10.80 |
| 2026-04-29 | DNLI | -0.31 | 7.63 | 10.79 |
| 2026-04-30 | DNLI | -0.31 | 7.63 | 10.79 |
| 2026-05-01 | DNLI | -0.31 | 7.63 | 10.79 |
| 2026-05-04 | DNLI | -0.31 | 5.97 | 10.79 |
| 2026-05-05 | DNLI | -0.31 | 5.97 | 10.79 |
| 2026-05-06 | DNLI | -0.31 | 5.97 | 10.79 |
| 2026-05-07 | DNLI | -0.31 | 5.97 | 10.79 |
| 2026-05-08 | DNLI | -0.31 | 5.97 | 10.79 |
| 2026-05-11 | DNLI | -0.31 | 5.19 | 10.79 |
| 2026-05-12 | DNLI | -0.31 | 5.19 | 10.46 |
| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
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Last Quarter Act. EPS
-0.69
Avg. EPS Est. Current Quarter
-0.53
Avg. EPS Est. Next Quarter
-0.64
Insider Transactions
-0.31
Institutional Transactions
5.19
Beta
1
Average Sales Estimate Current Quarter
19
Average Sales Estimate Next Quarter
20
Fair Value
Quality Score
6
Growth Score
22
Sentiment Score
94
Actual DrawDown %
75.6
Max Drawdown 5-Year %
-85.4
Target Price
35.27
P/E
Forward P/E
PEG
P/S
P/B
3.33
P/Free Cash Flow
EPS
-2.88
Average EPS Est. Cur. Y
-2.35
EPS Next Y. (Est.)
-2.56
Target Price Estimates Raised
Target Price Estimates Lowered
1
Profit Margin
Relative Volume
1.02
Return on Equity vs Sector %
-81.7
Return on Equity vs Industry %
-66.2
EPS 1 7Days Diff
0.2
EPS 1 30Days Diff
0.13
EBIT Estimation
◆
DNLI
Healthcare
$19.46
📉
N/A
Swing / Pullback
Buy the dip on strong trends
WEAK
Trend
14/20
Pullback
19/25
Volume
4/15
Valuation
10/20
TP/AR
4/10
Options
7/10
RSI
48.4
Range 1M
36%
Sup Dist
1.2%
🚀
N/A
Momentum Growth
Ride accelerating trends
WEAK
Momentum
8/25
Growth
14/30
Estimates
2/20
Inst/Vol
7/15
Options
5/10
EPS Yr
16.5%
EPS NY
1%
52W%
61.2%
💎
N/A
Long-Term Value
Quality companies, undervalued
WEAK
🟢 BUY
+81.2% upside
Quality
2/30
Valuation
16/30
Growth
10/25
Stability
9/10
LT Trend
1/5
Upside
+81.2%
Quality
6
Click a card to see score breakdown
Full Analysis →
Sector: Healthcare
Industry: Biotechnology
Employees: 507
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
DNLI
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