DNLI – Denali Therapeutics Inc.
Float Short %
9.42
Margin Of Safety %
Put/Call OI Ratio
0.21
EPS Next Q Diff
-0.03
EPS Last/This Y
-0.44
EPS This/Next Y
0.04
Price
16.95
Target Price
32.29
Analyst Recom
1.06
Performance Q
13.76
Relative Volume
1.18
Beta
1.02
Ticker: DNLI
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| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
|---|---|---|---|---|---|
| 2025-12-09 | DNLI | 18.97 | 0.48 | 0.77 | 2257 |
| 2025-12-10 | DNLI | 17.55 | 0.48 | 5.87 | 2265 |
| 2025-12-11 | DNLI | 17.35 | 0.70 | 0.06 | 2637 |
| 2025-12-12 | DNLI | 18 | 0.67 | 0.00 | 2720 |
| 2025-12-15 | DNLI | 17.35 | 0.66 | 0.36 | 2735 |
| 2025-12-16 | DNLI | 17.01 | 0.66 | 0.06 | 2767 |
| 2025-12-17 | DNLI | 16.82 | 0.64 | 0.11 | 2830 |
| 2025-12-18 | DNLI | 16.76 | 0.64 | 0.21 | 2853 |
| 2025-12-19 | DNLI | 16.86 | 0.63 | 0.02 | 2862 |
| 2025-12-22 | DNLI | 17.49 | 0.20 | 0.00 | 2474 |
| 2025-12-23 | DNLI | 16.82 | 0.19 | 1.00 | 2539 |
| 2025-12-26 | DNLI | 16.85 | 0.19 | 3.00 | 2578 |
| 2025-12-29 | DNLI | 16.58 | 0.22 | 0.00 | 2637 |
| 2025-12-30 | DNLI | 16.41 | 0.21 | 0.09 | 2742 |
| 2025-12-31 | DNLI | 16.51 | 0.20 | 0.01 | 2749 |
| 2026-01-02 | DNLI | 16.29 | 0.20 | 0.92 | 2825 |
| 2026-01-05 | DNLI | 16.03 | 0.21 | 0.13 | 2890 |
| 2026-01-06 | DNLI | 17.2 | 0.21 | 0.04 | 2895 |
| 2026-01-07 | DNLI | 16.96 | 0.21 | 0.00 | 2909 |
| Date | Symbol | Latest | P/C OI | P/C Vol | Total OI |
Current Page1 of 1
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| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
|---|---|---|---|---|---|
| 2025-12-09 | DNLI | 19.66 | -14.1 | 215.2 | -3.01 |
| 2025-12-10 | DNLI | 17.55 | -14.1 | 264.0 | -3.01 |
| 2025-12-11 | DNLI | 17.36 | -14.1 | 220.0 | -3.01 |
| 2025-12-12 | DNLI | 17.99 | -14.1 | 197.4 | -3.01 |
| 2025-12-15 | DNLI | 17.34 | -14.1 | 231.0 | -3.01 |
| 2025-12-16 | DNLI | 17.34 | -14.1 | 223.6 | -3.01 |
| 2025-12-17 | DNLI | 16.80 | -14.1 | 220.0 | -3.01 |
| 2025-12-18 | DNLI | 16.76 | -14.1 | 216.2 | -3.01 |
| 2025-12-19 | DNLI | 16.86 | -14.1 | 211.8 | -3.01 |
| 2025-12-22 | DNLI | 17.41 | -14.1 | 198.4 | -3.01 |
| 2025-12-23 | DNLI | 16.75 | -14.1 | 234.0 | -3.01 |
| 2025-12-26 | DNLI | 16.88 | -14.1 | 217.5 | -3.01 |
| 2025-12-29 | DNLI | 16.58 | -14.1 | 222.5 | -3.01 |
| 2025-12-30 | DNLI | 16.42 | -14.1 | 218.9 | -3.01 |
| 2025-12-31 | DNLI | 16.52 | -14.1 | 211.1 | -3.01 |
| 2026-01-02 | DNLI | 16.29 | -14.1 | 220.7 | -3.01 |
| 2026-01-05 | DNLI | 16.01 | -14.1 | 222.1 | -3.01 |
| 2026-01-06 | DNLI | 17.21 | -14.1 | 178.1 | -3.01 |
| 2026-01-07 | DNLI | 16.95 | -14.1 | 221.2 | -3.01 |
| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
Current Page1 of 1
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| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
|---|---|---|---|---|
| 2025-12-09 | DNLI | -3.00 | 1.75 | 10.74 |
| 2025-12-10 | DNLI | -3.00 | 1.75 | 9.95 |
| 2025-12-11 | DNLI | -3.00 | 1.75 | 9.95 |
| 2025-12-12 | DNLI | -3.00 | 1.75 | 9.95 |
| 2025-12-15 | DNLI | -2.83 | 1.69 | 9.34 |
| 2025-12-16 | DNLI | -2.84 | 1.69 | 9.34 |
| 2025-12-17 | DNLI | -2.84 | 1.69 | 9.34 |
| 2025-12-18 | DNLI | -2.84 | 1.69 | 9.34 |
| 2025-12-19 | DNLI | -2.84 | 1.69 | 9.34 |
| 2025-12-22 | DNLI | -2.84 | 1.34 | 9.34 |
| 2025-12-23 | DNLI | -2.84 | 1.34 | 9.34 |
| 2025-12-26 | DNLI | -2.84 | 1.34 | 9.42 |
| 2025-12-29 | DNLI | -2.84 | 1.34 | 9.42 |
| 2025-12-30 | DNLI | -2.84 | 1.34 | 9.42 |
| 2025-12-31 | DNLI | -2.84 | 1.34 | 9.42 |
| 2026-01-02 | DNLI | -2.84 | 1.34 | 9.42 |
| 2026-01-05 | DNLI | -2.84 | 1.34 | 9.42 |
| 2026-01-06 | DNLI | -2.84 | 1.34 | 9.42 |
| 2026-01-07 | DNLI | -2.84 | 1.34 | 9.42 |
| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
Current Page1 of 1
Last Quarter Act. EPS
-0.74
Avg. EPS Est. Current Quarter
-0.76
Avg. EPS Est. Next Quarter
-0.77
Insider Transactions
-2.84
Institutional Transactions
1.34
Beta
1.02
Average Sales Estimate Current Quarter
2
Average Sales Estimate Next Quarter
1
Fair Value
Quality Score
7
Growth Score
23
Sentiment Score
36
Actual DrawDown %
79.8
Max Drawdown 5-Year %
-85.9
Target Price
32.29
P/E
Forward P/E
PEG
P/S
P/B
2.68
P/Free Cash Flow
EPS
-2.91
Average EPS Est. Cur. Y
-3.01
EPS Next Y. (Est.)
-2.97
Target Price Estimates Raised
Target Price Estimates Lowered
Profit Margin
Relative Volume
1.18
Return on Equity vs Sector %
-80.9
Return on Equity vs Industry %
-65.8
EPS 1 7Days Diff
EPS 1 30Days Diff
-0.02
EBIT Estimation
221.2
Denali Therapeutics Inc.Sector: Healthcare
Industry: Biotechnology
Employees: 517
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
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