Denali Therapeutics Inc.

DNLI

$20.39

Name : Denali Therapeutics Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $3,259,288,576.00

EPSttm : -2.84

Denali Therapeutics Inc.

$20.39

0.39%

$0.08

DNLI — Price & Float Short

—— Fair value ★ EPS beat ★ EPS miss —— Target Price

Float Short %

11.45

Margin Of Safety %

Put/Call OI Ratio

1.36

EPS Next Q Diff

0.06

EPS Last/This Y

0.75

EPS This/Next Y

-0.2

Price

20.4

Target Price

36.06

Analyst Recom

1.15

Performance Q

-20.26

Upside

-281.1%

Beta

1.02

Ticker: DNLI

19 items of 1

Date	Symbol	Latest	P/C OI	P/C Vol	Total OI
2026-08-28	DNLI	24	1.75	1.84	11374
2026-08-31	DNLI	23.75	1.76	1.22	11673
2026-09-02	DNLI	22.86	1.54	1.03	12463
2026-09-03	DNLI	22.8	1.49	1.52	12634
2026-09-04	DNLI	22.28	1.50	2.03	12913
2026-09-08	DNLI	22	1.46	1.61	13155
2026-09-09	DNLI	21.58	1.44	1.07	13471
2026-09-10	DNLI	21.4	1.41	1.07	13584
2026-09-11	DNLI	21.07	1.41	0.23	13683
2026-09-14	DNLI	21.21	1.37	0.31	13877
2026-09-15	DNLI	20.38	1.38	0.40	13862
2026-09-16	DNLI	20.06	1.33	0.01	13700
2026-09-17	DNLI	20.12	1.34	0.51	13683
2026-09-18	DNLI	19.66	1.23	3.08	13819
2026-09-21	DNLI	20.48	1.66	0.47	10113
2026-09-22	DNLI	21.61	1.46	0.25	10721
2026-09-23	DNLI	20.46	1.34	7.31	11128
2026-09-24	DNLI	20.48	1.35	40.47	11221
2026-09-25	DNLI	20.41	1.36	0.48	11299
Date	Symbol	Latest	P/C OI	P/C Vol	Total OI

19 items 1 of 1

20 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2026-08-28	DNLI	24.01	45.2	-	-2.29
2026-08-31	DNLI	23.74	43.2	-	-2.35
2026-09-01	DNLI	23.26	43.2	-	-2.35
2026-09-02	DNLI	22.87	43.2	-	-2.35
2026-09-03	DNLI	22.79	43.2	-	-2.35
2026-09-04	DNLI	22.29	43.2	-	-2.35
2026-09-08	DNLI	22.08	43.2	-	-2.35
2026-09-09	DNLI	21.59	43.2	-	-2.35
2026-09-10	DNLI	21.40	43.2	-	-2.35
2026-09-11	DNLI	21.06	43.2	-	-2.35
2026-09-14	DNLI	21.21	43.2	-	-2.35
2026-09-15	DNLI	20.38	43.2	-	-2.35
2026-09-16	DNLI	20.38	43.2	-	-2.35
2026-09-17	DNLI	20.12	50.6	-	-2.22
2026-09-18	DNLI	19.73	50.6	-	-2.22
2026-09-21	DNLI	20.48	50.6	-	-2.22
2026-09-22	DNLI	21.61	50.6	-	-2.22
2026-09-23	DNLI	20.45	50.6	-	-2.22
2026-09-24	DNLI	20.48	50.6	-	-2.22
2026-09-25	DNLI	20.40	50.6	-	-2.22
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

20 items 1 of 1

19 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2026-08-28	DNLI	-0.03	2.29	12.00
2026-08-31	DNLI	-0.03	2.25	12.00
2026-09-01	DNLI	-0.03	2.25	12.00
2026-09-02	DNLI	-0.03	2.25	12.00
2026-09-03	DNLI	-0.03	2.25	12.00
2026-09-04	DNLI	-0.05	2.25	12.00
2026-09-08	DNLI	-0.17	2.29	12.00
2026-09-09	DNLI	-0.17	2.29	12.00
2026-09-10	DNLI	-0.18	2.29	12.00
2026-09-11	DNLI	-0.18	2.29	11.12
2026-09-14	DNLI	-0.18	2.29	11.12
2026-09-15	DNLI	-0.18	2.29	11.12
2026-09-16	DNLI	-0.18	2.29	11.12
2026-09-17	DNLI	-0.18	2.29	11.12
2026-09-18	DNLI	-0.18	2.29	11.12
2026-09-21	DNLI	-0.18	2.29	11.12
2026-09-23	DNLI	-0.18	2.29	11.12
2026-09-24	DNLI	-0.18	2.29	11.12
2026-09-25	DNLI	-0.18	2.29	11.45
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

19 items 1 of 1

Last Quarter Act. EPS

-0.68

Avg. EPS Est. Current Quarter

-0.37

Avg. EPS Est. Next Quarter

-0.62

Insider Transactions

-0.18

Institutional Transactions

2.29

Beta

1.02

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

63.6

Max Drawdown 5-Year %

-79.2

Target Price

36.06

P/E

Forward P/E

PEG

P/S

905.36

P/B

3.9

P/Free Cash Flow

EPS

-2.84

Average EPS Est. Cur. Y

-2.22

EPS Next Y. (Est.)

-2.42

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

-14191.2

Relative Volume

0.74

Return on Equity vs Sector %

-87.5

Return on Equity vs Industry %

-67.9

EPS 1 7Days Diff

0.1

EPS 1 30Days Diff

0.07

EBIT Estimation

◆ DNLI Healthcare

$20.39

📉

Swing / Pullback

Buy the dip on strong trends

N/A

WEAK

Trend

10/20

Pullback

19/25

Volume

9/15

Valuation

10/20

TP/AR

2/10

Options

3/10

RSI

37.5

Range 1M

17.5%

Sup Dist

2.3%

🚀

Momentum Growth

Ride accelerating trends

N/A

WEAK

Momentum

3/25

Growth

12/30

Estimates

0/20

Inst/Vol

5/15

Options

6/10

EPS Yr

22.9%

EPS NY

-2.4%

52W%

50.5%

💎

Long-Term Value

Quality companies, undervalued

N/A

WEAK

🟢 BUY +76.9% upside

Quality

3/30

Valuation

14/30

Growth

10/25

Stability

9/10

LT Trend

3/5

Upside

+76.9%

Quality

DNLI — P/E HistoricalBiotechnology

Denali Therapeutics Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 503

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

DNLI

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Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Upside

Beta

Ticker: DNLI

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Latest News

Last Quarter Act. EPS

Average EPS Est. Cur. Y