Spero Therapeutics, Inc.

SPRO

$2.43

Name : Spero Therapeutics, Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $136,748,800.00

EPSttm : -0.98

Spero Therapeutics, Inc.

$2.43

0.83%

$0.02

Float Short %

1.17

Margin Of Safety %

Put/Call OI Ratio

0.12

EPS Next Q Diff

EPS Last/This Y

0.81

EPS This/Next Y

0.43

Price

2.43

Target Price

Analyst Recom

Performance Q

32.07

Relative Volume

0.99

Beta

1.48

Ticker: SPRO

21 items of 1

Date	Symbol	Last	P/C OI	P/C Vol	Total OI
2025-10-20	SPRO	2.29	0.09	0.03	7663
2025-10-21	SPRO	2.35	0.09	0.02	8051
2025-10-22	SPRO	2.25	0.08	0.09	8565
2025-10-23	SPRO	2.2	0.11	0.00	8789
2025-10-24	SPRO	2.21	0.11	0.73	8997
2025-10-27	SPRO	2.29	0.12	0.22	9218
2025-10-28	SPRO	2.38	0.12	0.00	9481
2025-10-29	SPRO	2.33	0.12	0.00	9761
2025-10-30	SPRO	2.37	0.11	1.39	9948
2025-10-31	SPRO	2.43	0.12	0.00	10027
2025-11-03	SPRO	2.37	0.12	0.00	10302
2025-11-04	SPRO	2.36	0.11	0.00	10390
2025-11-05	SPRO	2.42	0.11	0.00	10338
2025-11-06	SPRO	2.38	0.11	0.33	10373
2025-11-07	SPRO	2.45	0.11	0.00	10428
2025-11-10	SPRO	2.51	0.11	0.05	10409
2025-11-11	SPRO	2.62	0.11	0.00	10513
2025-11-12	SPRO	2.66	0.11	0.03	10511
2025-11-13	SPRO	2.46	0.11	0.39	10812
2025-11-14	SPRO	2.4	0.11	0.27	10907
2025-11-17	SPRO	2.43	0.12	0.25	11124
Date	Symbol	Last	P/C OI	P/C Vol	Total OI

21 items 1 of 1

21 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2025-10-20	SPRO	2.29	-	-	-0.46
2025-10-21	SPRO	2.37	-	-	-0.46
2025-10-22	SPRO	2.25	-	-	-0.46
2025-10-23	SPRO	2.20	-	-	-0.46
2025-10-24	SPRO	2.22	-	-	-0.46
2025-10-27	SPRO	2.30	-	-	-0.46
2025-10-28	SPRO	2.38	-	-	-0.46
2025-10-29	SPRO	2.33	-	-	-0.46
2025-10-30	SPRO	2.36	-	-	-0.46
2025-10-31	SPRO	2.43	-	-	-0.46
2025-11-03	SPRO	2.37	-	-	-0.46
2025-11-04	SPRO	2.36	-	-	-0.46
2025-11-05	SPRO	2.42	-	-	-0.46
2025-11-06	SPRO	2.38	-	-	-0.46
2025-11-07	SPRO	2.46	-	-	-0.46
2025-11-10	SPRO	2.50	-	-	-0.46
2025-11-11	SPRO	2.62	-	-	-0.46
2025-11-12	SPRO	2.66	-	-	-0.46
2025-11-13	SPRO	2.46	-	-	-0.46
2025-11-14	SPRO	2.41	-	-	-0.46
2025-11-17	SPRO	2.43	-	-	-0.46
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

21 items 1 of 1

21 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2025-10-20	SPRO	-0.05	-7.29	1.42
2025-10-21	SPRO	-0.05	-7.29	1.42
2025-10-22	SPRO	-0.05	-7.29	1.42
2025-10-23	SPRO	-0.05	-7.29	1.42
2025-10-24	SPRO	-0.05	-7.29	1.42
2025-10-27	SPRO	-0.05	-7.17	0.82
2025-10-28	SPRO	-0.05	-7.17	0.82
2025-10-29	SPRO	-0.05	-7.17	0.82
2025-10-30	SPRO	-0.05	-7.17	0.82
2025-10-31	SPRO	-0.05	-7.17	0.82
2025-11-03	SPRO	-0.05	-7.29	0.78
2025-11-04	SPRO	-0.05	-7.29	0.78
2025-11-05	SPRO	-0.05	-7.29	0.78
2025-11-06	SPRO	-0.05	-7.29	0.78
2025-11-07	SPRO	-0.05	-7.29	0.78
2025-11-10	SPRO	-0.05	-7.24	0.78
2025-11-11	SPRO	-0.05	-7.24	0.78
2025-11-12	SPRO	-0.05	-7.24	1.18
2025-11-13	SPRO	-0.30	-7.24	1.18
2025-11-14	SPRO	-0.30	-7.24	1.17
2025-11-17	SPRO	-0.31	-4.69	1.17
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

21 items 1 of 1

Last Quarter Act. EPS

Avg. EPS Est. Current Quarter

-0.22

Avg. EPS Est. Next Quarter

-0.2

Insider Transactions

-0.31

Institutional Transactions

-4.69

Beta

1.48

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

89.7

Max Drawdown 5-Year %

-97.5

Target Price

P/E

Forward P/E

162

PEG

P/S

4.67

P/B

5.16

P/Free Cash Flow

EPS

-0.79

Average EPS Est. Cur. Y

-0.46

EPS Next Y. (Est.)

-0.04

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

-149.52

Relative Volume

0.99

Return on Equity vs Sector %

-190.2

Return on Equity vs Industry %

-175.3

EPS 1 7Days Diff

0.3

EPS 1 30Days Diff

0.69

EBIT Estimation

Spero Therapeutics, Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 32

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candidate for first-line treatment of nontuberculous mycobacterial (NTM) pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to the oral prodrug SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

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Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Relative Volume

Beta

Ticker: SPRO

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Last Quarter Act. EPS

Average EPS Est. Cur. Y