Spero Therapeutics, Inc.

SPRO

$2.51

Name : Spero Therapeutics, Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $141,411,632.00

EPSttm : -0.79

Spero Therapeutics, Inc.

$2.51

3.29%

$0.08

Float Short %

2.58

Margin Of Safety %

Put/Call OI Ratio

0.15

EPS Next Q Diff

EPS Last/This Y

1.17

EPS This/Next Y

0.77

Price

2.51

Target Price

Analyst Recom

Performance Q

20.1

Relative Volume

0.44

Beta

1.45

Ticker: SPRO

19 items of 1

Date	Symbol	Latest	P/C OI	P/C Vol	Total OI
2025-12-08	SPRO	2.31	0.09	0.00	9682
2025-12-09	SPRO	2.32	0.09	0.00	9821
2025-12-10	SPRO	2.34	0.09	0.00	9827
2025-12-11	SPRO	2.36	0.09	0.00	9972
2025-12-12	SPRO	2.32	0.09	0.00	10004
2025-12-15	SPRO	2.3	0.09	0.00	10060
2025-12-16	SPRO	2.29	0.09	0.00	10171
2025-12-17	SPRO	2.32	0.09	0.00	10231
2025-12-18	SPRO	2.31	0.08	0.03	10565
2025-12-19	SPRO	2.34	0.08	0.00	10572
2025-12-22	SPRO	2.37	0.08	0.01	9650
2025-12-23	SPRO	2.33	0.08	0.09	9897
2025-12-26	SPRO	2.32	0.08	0.38	10269
2025-12-29	SPRO	2.29	0.08	3.98	10162
2025-12-30	SPRO	2.29	0.14	0.00	10880
2025-12-31	SPRO	2.33	0.14	0.02	10910
2026-01-02	SPRO	2.35	0.14	0.05	10931
2026-01-05	SPRO	2.43	0.14	1.59	11488
2026-01-06	SPRO	2.51	0.15	0.82	11500
Date	Symbol	Latest	P/C OI	P/C Vol	Total OI

19 items 1 of 1

19 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2025-12-08	SPRO	2.31	-	-	-0.65
2025-12-09	SPRO	2.33	-	-	-0.65
2025-12-10	SPRO	2.34	-	-	-0.65
2025-12-11	SPRO	2.35	-	-	-0.65
2025-12-12	SPRO	2.33	-	-	-0.13
2025-12-15	SPRO	2.29	-	-	-0.13
2025-12-16	SPRO	2.29	-	-	-0.13
2025-12-17	SPRO	2.32	-	-	-0.13
2025-12-18	SPRO	2.30	-	-	-0.13
2025-12-19	SPRO	2.34	-	-	-0.10
2025-12-22	SPRO	2.36	-	-	-0.10
2025-12-23	SPRO	2.34	-	-	-0.10
2025-12-26	SPRO	2.32	-	-	-0.10
2025-12-29	SPRO	2.29	-	-	-0.10
2025-12-30	SPRO	2.28	-	-	-0.10
2025-12-31	SPRO	2.33	-	-	-0.10
2026-01-02	SPRO	2.35	-	-	-0.10
2026-01-05	SPRO	2.43	-	-	-0.10
2026-01-06	SPRO	2.51	-	-	-0.10
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

19 items 1 of 1

19 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2025-12-08	SPRO	-0.31	0.25	1.51
2025-12-09	SPRO	-0.31	0.25	1.51
2025-12-10	SPRO	-0.31	0.25	2.02
2025-12-11	SPRO	-0.31	0.25	2.02
2025-12-12	SPRO	-0.31	0.25	2.02
2025-12-15	SPRO	-0.31	0.25	2.02
2025-12-16	SPRO	-0.31	0.25	2.02
2025-12-17	SPRO	-0.31	0.25	2.02
2025-12-18	SPRO	-0.31	0.25	2.02
2025-12-19	SPRO	-0.31	0.25	2.02
2025-12-22	SPRO	-0.31	0.26	2.02
2025-12-23	SPRO	-0.31	0.26	2.02
2025-12-26	SPRO	-0.31	0.26	2.58
2025-12-29	SPRO	-0.31	0.26	2.58
2025-12-30	SPRO	-0.31	0.26	2.58
2025-12-31	SPRO	-0.31	0.26	2.58
2026-01-02	SPRO	-0.31	0.26	2.58
2026-01-05	SPRO	-0.31	0.26	2.58
2026-01-06	SPRO	-0.31	0.26	2.58
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

19 items 1 of 1

Last Quarter Act. EPS

-0.13

Avg. EPS Est. Current Quarter

-0.2

Avg. EPS Est. Next Quarter

Insider Transactions

-0.31

Institutional Transactions

0.26

Beta

1.45

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

88.7

Max Drawdown 5-Year %

-97.4

Target Price

P/E

Forward P/E

3.75

PEG

P/S

4.82

P/B

5.33

P/Free Cash Flow

EPS

-0.79

Average EPS Est. Cur. Y

-0.1

EPS Next Y. (Est.)

0.67

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

-149.52

Relative Volume

0.44

Return on Equity vs Sector %

-192.5

Return on Equity vs Industry %

-177.4

EPS 1 7Days Diff

EPS 1 30Days Diff

0.29

EBIT Estimation

Spero Therapeutics, Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 32

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candidate for first-line treatment of nontuberculous mycobacterial (NTM) pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to the oral prodrug SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

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Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Relative Volume

Beta

Ticker: SPRO

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Last Quarter Act. EPS

Average EPS Est. Cur. Y