Ionis Pharmaceuticals, Inc.

IONS

$73.26

Name : Ionis Pharmaceuticals, Inc.

Sector : Healthcare

Industry: Biotechnology

Mark. Cap: $11,866,245,120.00

EPSttm : -1.61

Ionis Pharmaceuticals, Inc.

$73.26

2.39%

$1.71

Float Short %

7.87

Margin Of Safety %

Put/Call OI Ratio

0.62

EPS Next Q Diff

0.11

EPS Last/This Y

1.37

EPS This/Next Y

-0.52

Price

73.32

Target Price

84.18

Analyst Recom

1.6

Performance Q

72.46

Relative Volume

1.29

Beta

0.32

Ticker: IONS

21 items of 1

Date	Symbol	Last	P/C OI	P/C Vol	Total OI
2025-10-20	IONS	73.55	0.54	0.09	28008
2025-10-21	IONS	71.65	0.54	0.14	28080
2025-10-22	IONS	71.49	0.54	0.54	28202
2025-10-23	IONS	71.47	0.54	7.22	28261
2025-10-24	IONS	70.83	0.55	0.21	28371
2025-10-27	IONS	72.99	0.54	0.68	28756
2025-10-28	IONS	73.61	0.57	0.21	29327
2025-10-29	IONS	71.88	0.56	0.45	29612
2025-10-30	IONS	74.16	0.56	0.53	30018
2025-10-31	IONS	74.28	0.56	0.31	30357
2025-11-03	IONS	73.64	0.55	0.21	31492
2025-11-04	IONS	72.88	0.55	0.81	31511
2025-11-05	IONS	74.65	0.56	0.72	32411
2025-11-06	IONS	74.1	0.56	0.06	32559
2025-11-07	IONS	73.55	0.55	0.52	32815
2025-11-10	IONS	69.54	0.54	0.48	34188
2025-11-11	IONS	72.36	0.54	0.07	35188
2025-11-12	IONS	73.07	0.55	5.51	34789
2025-11-13	IONS	69.81	0.56	2.43	35432
2025-11-14	IONS	71.58	0.61	0.48	36363
2025-11-17	IONS	73.28	0.62	0.56	36851
Date	Symbol	Last	P/C OI	P/C Vol	Total OI

21 items 1 of 1

21 items of 1

Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year
2025-10-20	IONS	73.55	-42.4	-318.5	-1.92
2025-10-21	IONS	71.65	-42.4	-300.9	-1.92
2025-10-22	IONS	71.50	-42.4	-314.0	-1.92
2025-10-23	IONS	71.51	-42.4	-315.1	-1.92
2025-10-24	IONS	70.84	-42.4	-310.0	-1.92
2025-10-27	IONS	72.99	-42.4	-331.6	-1.92
2025-10-28	IONS	73.57	-48.6	-319.4	-1.93
2025-10-29	IONS	71.91	-48.6	-302.7	-1.93
2025-10-30	IONS	74.17	-45.2	-328.1	-1.93
2025-10-31	IONS	74.30	-45.2	-317.3	-1.93
2025-11-03	IONS	73.65	-221.4	-311.8	-1.80
2025-11-04	IONS	72.87	-189.1	-310.9	-1.63
2025-11-05	IONS	74.66	-189.1	-329.2	-1.63
2025-11-06	IONS	74.10	-189.1	-208.0	-1.63
2025-11-07	IONS	73.55	-189.1	-208.1	-1.63
2025-11-10	IONS	69.54	-178.1	-188.8	-1.63
2025-11-11	IONS	72.45	-178.1	-228.4	-1.61
2025-11-12	IONS	72.70	-178.1	-212.6	-1.61
2025-11-13	IONS	69.83	-178.1	-195.1	-1.61
2025-11-14	IONS	71.60	-178.1	-221.6	-1.61
2025-11-17	IONS	73.32	-186.1	-221.4	-1.67
Date	Ticker	Price	Current Quarter Growth Estimate	EBIT Estimation	Average EPS Estimate Current Year

21 items 1 of 1

21 items of 1

Date	Ticker	Insider Transactions	Institutional Transactions	Float Short
2025-10-20	IONS	-43.64	1.00	7.76
2025-10-21	IONS	-43.64	1.00	7.76
2025-10-22	IONS	-43.97	1.00	7.76
2025-10-23	IONS	-43.97	1.00	7.76
2025-10-24	IONS	-43.97	1.00	7.76
2025-10-27	IONS	-43.97	1.17	8.66
2025-10-28	IONS	-43.97	1.17	8.66
2025-10-29	IONS	-42.38	1.17	8.66
2025-10-30	IONS	-42.38	1.17	8.66
2025-10-31	IONS	-42.38	1.17	8.66
2025-11-03	IONS	-43.96	1.07	8.52
2025-11-04	IONS	-47.24	1.07	8.52
2025-11-05	IONS	-47.24	1.07	8.52
2025-11-06	IONS	-47.24	1.07	8.52
2025-11-07	IONS	-48.20	1.07	8.52
2025-11-10	IONS	-48.20	0.68	8.52
2025-11-11	IONS	-49.22	0.68	8.52
2025-11-12	IONS	-49.22	0.68	7.87
2025-11-13	IONS	-49.22	0.68	7.87
2025-11-14	IONS	-49.22	0.68	7.87
2025-11-17	IONS	-49.57	3.49	7.87
Date	Ticker	Insider Transactions	Institutional Transactions	Float Short

21 items 1 of 1

Last Quarter Act. EPS

-0.8

Avg. EPS Est. Current Quarter

-1.23

Avg. EPS Est. Next Quarter

-0.69

Insider Transactions

-49.57

Institutional Transactions

3.49

Beta

0.32

Average Sales Estimate Current Quarter

152

Average Sales Estimate Next Quarter

188

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

4.5

Max Drawdown 5-Year %

-60

Target Price

84.18

P/E

Forward P/E

PEG

P/S

12.27

P/B

19.1

P/Free Cash Flow

EPS

-1.71

Average EPS Est. Cur. Y

-1.67

EPS Next Y. (Est.)

-2.2

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

-26.46

Relative Volume

1.29

Return on Equity vs Sector %

-68.4

Return on Equity vs Industry %

-53.5

EPS 1 7Days Diff

EPS 1 30Days Diff

0.25

EBIT Estimation

-221.4

Ionis Pharmaceuticals, Inc.

Sector: Healthcare

Industry: Biotechnology

Employees: 1069

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSEDI for the treatment of ATTRv-PN in adults; and WAYLIVRA for treatment for FCS and familial partial lipodystrophy. It also develops products under Phase 3 clinical trials, such as Olezarsen for patients with hypertriglyceridemia (SHTG) and cardiovascular disease (CVD); Donidalorsen for patients with hereditary angioedema; and Zilganerse, a potential treatment for people with genetically confirmed Alexander disease, as well as ION582 that has completed Phase 2 clinical trial for the potential treatment of AS, a rare genetic neurological disease. In addition, the company develops Eplontersen to degrade mutant and wild-type TTR mRNA through binding to the TTR mRNA; Pelacarsen to inhibit the production of apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a); Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus; Sefaxersen to reduce the production of complement factor B and lower activation of the alternative complement pathway; and Ulefnersen to reduce the production of the fused in sarcoma, as well as other mid-stage pipeline investigational medicines. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with GSK, AstraZeneca, Novartis, and Roche, as well as with Metagenomi. The company was incorporated in 1989 and is headquartered in Carlsbad, California.

stock quote shares IONS – Ionis Pharmaceuticals, Inc. Stock Price stock today

news today IONS – Ionis Pharmaceuticals, Inc. stock forecast ,stock prediction 2023 2024 2025

marketwatch IONS – Ionis Pharmaceuticals, Inc. yahoo finance google finance

stock history IONS – Ionis Pharmaceuticals, Inc. invest stock market

stock prices IONS premarket after hours

ticker IONS fair value insiders trading

Float Short %

Margin Of Safety %

Put/Call OI Ratio

EPS Next Q Diff

EPS Last/This Y

EPS This/Next Y

Price

Target Price

Analyst Recom

Performance Q

Relative Volume

Beta

Ticker: IONS

Last Quarter Act. EPS​

Avg. EPS Est. Current Quarter

Avg. EPS Est. Next Quarter

Insider Transactions

Institutional Transactions

Beta

Average Sales Estimate Current Quarter

Average Sales Estimate Next Quarter

Fair Value

Quality Score

Growth Score

Sentiment Score

Actual DrawDown %

Max Drawdown 5-Year %

Target Price

P/E

Forward P/E

PEG

P/S

P/B

P/Free Cash Flow

EPS

Average EPS Est. Cur. Y​

EPS Next Y. (Est.)

Target Price Estimates Raised

Target Price Estimates Lowered

Profit Margin

Relative Volume

Return on Equity vs Sector %

Return on Equity vs Industry %

EPS 1 7Days Diff

EPS 1 30Days Diff

EBIT Estimation

Last Quarter Act. EPS

Average EPS Est. Cur. Y