PTGX – Protagonist Therapeutics Inc
PTGX
$85.08Name : Protagonist Therapeutics, Inc.
Sector : Healthcare
Industry: Biotechnology
Mark. Cap: $5,318,519,808.00
EPSttm : 0.66
Protagonist Therapeutics, Inc.
$85.08
Float Short %
9.25
Margin Of Safety %
-32
Put/Call OI Ratio
0.32
EPS Next Q Diff
0.16
EPS Last/This Y
-6.34
EPS This/Next Y
2.19
Price
84.61
Target Price
89.86
Analyst Recom
1.21
Performance Q
50.52
Relative Volume
0.58
Beta
2.18
Ticker: PTGX
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| Date | Symbol | Last | P/C OI | P/C Vol | Total OI |
|---|---|---|---|---|---|
| 2025-10-20 | PTGX | 76.72 | 0.31 | 0.42 | 15164 |
| 2025-10-21 | PTGX | 74.96 | 0.31 | 0.54 | 15450 |
| 2025-10-22 | PTGX | 73.5 | 0.31 | 0.13 | 15734 |
| 2025-10-23 | PTGX | 74.06 | 0.31 | 1.79 | 15940 |
| 2025-10-24 | PTGX | 74.88 | 0.38 | 0.09 | 17551 |
| 2025-10-27 | PTGX | 75.14 | 0.38 | 0.56 | 17554 |
| 2025-10-28 | PTGX | 78.63 | 0.37 | 0.14 | 17604 |
| 2025-10-29 | PTGX | 76.67 | 0.37 | 0.42 | 17784 |
| 2025-10-30 | PTGX | 77.86 | 0.36 | 0.36 | 17795 |
| 2025-10-31 | PTGX | 78.69 | 0.37 | 0.76 | 17842 |
| 2025-11-03 | PTGX | 75.9 | 0.37 | 1.01 | 17898 |
| 2025-11-04 | PTGX | 76.68 | 0.37 | 1.44 | 17977 |
| 2025-11-05 | PTGX | 77.83 | 0.38 | 0.05 | 18068 |
| 2025-11-06 | PTGX | 79.83 | 0.37 | 0.46 | 18165 |
| 2025-11-07 | PTGX | 79.6 | 0.37 | 0.13 | 18264 |
| 2025-11-10 | PTGX | 83.26 | 0.37 | 0.04 | 18592 |
| 2025-11-11 | PTGX | 85.56 | 0.32 | 0.03 | 20686 |
| 2025-11-12 | PTGX | 84.86 | 0.32 | 0.11 | 20803 |
| 2025-11-13 | PTGX | 83.31 | 0.32 | 0.29 | 20806 |
| 2025-11-14 | PTGX | 84.69 | 0.32 | 0.07 | 20953 |
| Date | Symbol | Last | P/C OI | P/C Vol | Total OI |
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| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
|---|---|---|---|---|---|
| 2025-10-20 | PTGX | 76.72 | -17.3 | - | -2.02 |
| 2025-10-21 | PTGX | 74.96 | -19.2 | - | -2.04 |
| 2025-10-22 | PTGX | 73.50 | -19.2 | - | -2.04 |
| 2025-10-23 | PTGX | 73.97 | -19.2 | - | -2.04 |
| 2025-10-24 | PTGX | 74.83 | -19.2 | - | -2.04 |
| 2025-10-27 | PTGX | 75.15 | -19.2 | - | -2.04 |
| 2025-10-28 | PTGX | 78.51 | -19.2 | - | -2.04 |
| 2025-10-29 | PTGX | 76.64 | -19.2 | - | -2.04 |
| 2025-10-30 | PTGX | 77.85 | -19.2 | - | -2.04 |
| 2025-10-31 | PTGX | 78.62 | -19.2 | - | -2.04 |
| 2025-11-03 | PTGX | 75.91 | -19.2 | - | -2.04 |
| 2025-11-04 | PTGX | 76.68 | -19.2 | - | -2.04 |
| 2025-11-05 | PTGX | 77.85 | -19.2 | - | -2.04 |
| 2025-11-06 | PTGX | 79.80 | -19.2 | - | -2.04 |
| 2025-11-07 | PTGX | 79.54 | -19.2 | - | -2.04 |
| 2025-11-10 | PTGX | 83.23 | -19.2 | - | -2.04 |
| 2025-11-11 | PTGX | 85.56 | -129.0 | - | -1.80 |
| 2025-11-12 | PTGX | 84.82 | -129.0 | - | -1.88 |
| 2025-11-13 | PTGX | 83.19 | -129.0 | - | -1.88 |
| 2025-11-14 | PTGX | 84.61 | -128.3 | - | -1.87 |
| Date | Ticker | Price | Current Quarter Growth Estimate | EBIT Estimation | Average EPS Estimate Current Year |
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| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
|---|---|---|---|---|
| 2025-10-20 | PTGX | -2.93 | 8.45 | 11.31 |
| 2025-10-21 | PTGX | -2.93 | 8.45 | 11.31 |
| 2025-10-22 | PTGX | -2.93 | 8.45 | 11.31 |
| 2025-10-23 | PTGX | -2.93 | 8.45 | 11.31 |
| 2025-10-24 | PTGX | -2.88 | 8.45 | 11.30 |
| 2025-10-27 | PTGX | -2.91 | 7.23 | 10.74 |
| 2025-10-28 | PTGX | -2.91 | 7.23 | 10.74 |
| 2025-10-29 | PTGX | -2.91 | 7.23 | 10.74 |
| 2025-10-30 | PTGX | -2.91 | 7.23 | 10.74 |
| 2025-10-31 | PTGX | -2.91 | 7.23 | 10.74 |
| 2025-11-03 | PTGX | -2.91 | 7.04 | 10.74 |
| 2025-11-04 | PTGX | -2.91 | 7.04 | 10.74 |
| 2025-11-05 | PTGX | -2.91 | 7.04 | 10.74 |
| 2025-11-06 | PTGX | -2.91 | 7.04 | 10.74 |
| 2025-11-07 | PTGX | -2.91 | 7.04 | 10.74 |
| 2025-11-10 | PTGX | -2.90 | 6.59 | 10.69 |
| 2025-11-11 | PTGX | -2.90 | 6.59 | 10.69 |
| 2025-11-12 | PTGX | -2.90 | 6.59 | 9.25 |
| 2025-11-13 | PTGX | -2.90 | 6.59 | 9.25 |
| 2025-11-14 | PTGX | -2.90 | 6.59 | 9.25 |
| Date | Ticker | Insider Transactions | Institutional Transactions | Float Short |
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Last Quarter Act. EPS
-0.62
Avg. EPS Est. Current Quarter
-0.56
Avg. EPS Est. Next Quarter
-0.46
Insider Transactions
-2.9
Institutional Transactions
6.59
Beta
2.18
Average Sales Estimate Current Quarter
31
Average Sales Estimate Next Quarter
51
Fair Value
57.49
Quality Score
54
Growth Score
59
Sentiment Score
97
Actual DrawDown %
9.3
Max Drawdown 5-Year %
-85.8
Target Price
89.86
P/E
133.58
Forward P/E
110.46
PEG
P/S
25.28
P/B
8.19
P/Free Cash Flow
83.02
EPS
0.63
Average EPS Est. Cur. Y
-1.87
EPS Next Y. (Est.)
0.32
Target Price Estimates Raised
3
Target Price Estimates Lowered
Profit Margin
21.94
Relative Volume
0.58
Return on Equity vs Sector %
-19.8
Return on Equity vs Industry %
-5
EPS 1 7Days Diff
0.2
EPS 1 30Days Diff
0.11
EBIT Estimation
Sector: Healthcare
Industry: Biotechnology
Employees: 128
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical trials indicated to block biological pathways targeted by marketed injectable antibody drugs; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
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